Escin phytosome 5 g

Eskin as an ingredient against swelling, cellulite and hair loss

Eskin is a natural mixture of triterpene saponins, with β-escin as the active ingredient. It is traditionally used in care and therapeutic cosmetics to combat swelling, cellulite, venous dilation, skin inflammation and hair loss. On the skin, escine acts primarily to increase microcirculation, oxygenation of the skin and has a strong draining effect. In our store you can buy a special form of Phytosome Eskin β-sitosterol, which is a complex of Eskin with β-sitosterol and lecithin in the patented Phytosome® technology, which is recommended not only in body care, but also in facial and eye care products.

Characteristics of the component and specifics of use

INCI: Lecithin, Escin, Beta-Sitosterol

Appearance: light brown powder

Dosage (percentage of input into cosmetics): 0,5-2 %

Solubility: dispersible in water and glycerin. It is recommended to be introduced at temperatures up to 40°C, but the component remains stable at temperatures up to 80°C.

Specifics of use: disperse in water and/or glycerine before emulsification. It is recommended to make water-glycerin premix at room temperature, observing the proportion of escin:glycerin:water -1:2:2:2. Mix the components under vigorous stirring for 30 minutes at room temperature until complete homogenization without any particles and add it immediately after emulsification. Stable at pH 3.0 to 8.0.

Storage: long term storage is recommended in a dark, dry place, hermetically sealed container at 10-30 °C.

Microcirculation and the skin

Microcirculation plays a significant role in skin homeostasis (transportation of gases, nutrients, waste products, hormones), in body thermoregulation, in blood pressure regulation and in the inflammatory response. When blood cannot flow freely to even the smallest blood vessels, the supply of oxygen and nutrients to them will be inadequate. As a result, the skin, lacking nutrients, becomes dull, pale and skin ischemia, cellulite, venous insufficiency and alopecia may occur. If the capillaries are too permeable to fluid, water seeps into the tissues and can also appear edema, cellulite, swelling, heaviness in the legs. And this is where escin comes to the rescue.

Eskin and its benefits

Eskin is a natural mixture of triterpene saponins, is produced from the seeds of Aesculus ippocastanum L., horse chestnut and has traditionally been used in health care and cosmetology for its anti-edema properties. In the skin, aescin acts primarily on the microcirculation through a complex set of mechanisms leading to increased microcirculation, oxygenation and drainage activity. The main molecular mechanism of action of aescin is selective vascular permeability: it causes selective sensitization of vascular smooth muscles to Ca2+ ions, which leads to increased venous tone and capillary thickening. Capillaries become less permeable to water, which provides increased microcirculation and anti-edema effect. It has also been observed to act in different ways: it counteracts the release of pro-inflammatory mediators (PGE2) at the vascular level and inhibits catabolic enzymes such as hyaluronidase, elastase, collagenase, cyclooxygenase.

Studies on the efficacy of phytosomes of estcine

Cellulite edema drainage efficacy and complx anti-cellulite activity (in vivo)

43 volunteers with cellulite received placebo or an active preparation containing escin-beta-sitosterol phytosomes (2%) as part of a

double-blind study. Volunteers administered the study drugs for 30 days. Clinical parameters: characteristic of cellulite and associated with impaired microcirculation, e.g. cold skin, squeezing pain. Results:

Statistically significant improvement in all symptoms associated with increased capillary wall fragility:

• Adipose tissue swelling: -50%
• Spontaneous pain (plaques): -60%
• Cold skin: -71.4%.

In a simple blind placebo controlled clinical trial, 25 volunteers with moderate cellulite applied the investigational drugs (active drug on one leg and placebo on the other) twice daily for 30 days. The combined strategy includes: Escin 1% - drainage, Visnadin 0.25% - microcirculation and Ginkgo biloba Dimeric flavonoids Phytosome (phytosomes with dimeric forms of ginkgo biloba flavonoids) 0.5% - lipolysis. Analyzed parameters: morphometric measurements (thigh circumference), clinical assessment of cellulite degree, thickness of subcutaneous fat measured by ultrasound. Results: there was a statistically significant decrease in thigh circumference compared to the placebo group, also subcutaneous fatty tissue decreased by 9.4% according to ultrasound. Statistically significant improvements were observed as follows:

• 23% improvement in appearance (upper third of the thigh)
• Squeezing pain (completely resolved) in the middle/lower third of the thigh: -100%
• Upper third of thigh: -82%.

Improvement of microcirculation (clinical evaluation) and skin oxygenation

When microcirculation is impaired, skin temperature becomes inhomogeneous, skin becomes dull and less oxygenated. This clinical study included a group of 20 women aged 17 to 64 years with signs of cellulite where impaired microcirculation was evident. They applied an emulsion containing 2% Escin phytosome. High Performance Contact Thermography (HPCT) was used to evaluate hypo-hyperthermic areas respectively before and 45-60 minutes after product application and massage, demonstrating microcirculation, which is directly related to skin temperature. Results: continuous improvement in thermo/vascular maps with a visible reduction in “cold zones”. The thermo-vascular map is characterized by a “leopard skin aspect” with pronounced distemper areas, where black represents T<31.05°C before application, resulting in a more homogeneous and warmer zone after application of the active formula. 

Microcirculation affects several functions of our body, not just cellulite. For example, in diabetic patients, impaired microcirculation can lead to ulcers and skin infections at the level of the lower limbs and feet, and 25% of diabetic patients may develop diabetic foot. The purpose of this clinical trial is to evaluate the ability of phytosomes escinum, used at a concentration of 1% in combination with Visnadin, Curbilene and ginger oil, to prevent skin lesions and ulcers in people with diabetic foot. 63 people with diabetic foot received the active formulation or standard treatment for 8 weeks. Evaluation included parameters such as resting blood flow assessed by laser Doppler flowmetry (LDF), skin oxygenation and clinical assessment of skin lesions. RESULTS: An improvement in peripheral skin microcirculation parameters was observed:

• Blood flow at rest -20%
• Occurrence of small skin lesions (<1 mm) -60%
• Occurrence of larger skin lesions -65%
• Oxygenation +4%.

Reduction of puffiness under the eyes (clinical evaluation)

The area around the eyes plays an important role in overall appearance, and it is one of the first areas to show signs of aging. The purpose of this clinical trial is to evaluate the efficacy of a formulation containing 0.2% pure escinum (or is it 0.5 phytosomes of escinum) on puffiness of the eyes, as assessed by the Mertz Aesthetics Scale (0 - no hollowness and 4 - very severe hollowness). Thirty-seven volunteers were randomized to apply either placebo or a mixture with escinum twice daily for 4-8 weeks. Results: statistically significant improvement in under-eye puffiness (assessed by the Mertz scale), an 8.34% reduction, particularly on the puffiness scale representing visible eye puffiness.

Clinical trials for eye puffiness were conducted using a multifunctional product based on Escin phytosome 1% containing other active ingredients such as Zanthalene at a concentration of 1% for immediate wrinkle smoothing, Ruscogenins to reduce dark circles under circles at a concentration of 0.1% and Ximilene. The active product and placebo were divided between 38 people to be applied twice a day for 4 weeks. Parameters such as microcirculation, skin temperature, transcutaneous oxygenation were evaluated to get a clear picture of the condition around the eyes. Results: an improvement in peripheral skin microcirculation parameters was observed:

Use in recipes and formulas

• anti-cellulite creams and body drainage cosmetics
• foot and leg care
• body care products
• eye cosmetics, especially for swelling under the eyes
• facial care cosmetics for oxygenation
• hair care products to counteract hair loss
• auxiliary cosmetics for microcirculation disorders.

Handmade cosmetics recipes and reviews

If you are new to cream-making - to make your own correct recipe is very difficult. And in this we are ready to help you. Go to youtube channel Cosmetic Kitchen Beurre, where we have already developed many recipes for handmade cosmetics and share the technology of making cosmetics with their own hands. And also go to the Blog from Beurre, where we share useful information about creating the right natural cosmetics.