SYN-AKE (SYN-AKE) 5 g
| Producer: | DSM |
| Appearance: | liquid |
| Solubility: | in water |
| Origin: | synthetic |
- Availability: In Stock
Syn-ake is a powerful peptide myorelaxant for smoothing expression wrinkles.
Syn-ake is a peptide of synthetic origin created by Swiss scientists. The company decided to create a peptide whose action would be different from the Argireline and Leuphasyl known to many, providing customers with a completely new ingredient that has an action similar to that of snake venom. Simply put, this peptide is a muscle nicotine receptor antagonist. This action allows the product to quickly and effectively smooth facial wrinkles.
Component Characteristics and Usage Peculiarities
INCI: water, glycerin, dipeptide diaminobutyroyl benzylamide diacetate
Dosage: 1 - 4%
Application: Dissolve in water in the active phase or inject immediately into a warm emulsion. It is recommended to administer the peptide at temperatures up to 40°C, but it remains stable at 70°C for 2 hours. The pH of the final product should be in the range of 3.0 - 7.5. Combination with up to 50% ethanol is acceptable.
Preservative: Ethylhexyl glycerin, phenoxyethanol.
Storage: Long-term storage is recommended at a temperature of +2 to 8 C. Temporary transport at other temperatures is allowed and does not affect the quality of the product. Do not freeze.
Use in Natural Cosmetics
Before you start creating innovative cosmetics with peptides, you need to understand what they are and how best to combine them for maximum results. For more information on this topic, read the article "Peptides in cosmetics: properties and uses" on the Beurre Store blog.
As for the peptide itself, Syn-ake was originally created to quickly and effectively smooth wrinkles and combat facial lines by relaxing facial muscles. This tripeptide works in much the same way as waglerin 1 by blocking muscle contractions. By acting at the postsynaptic membrane, the product becomes a reversible antagonist of the nicotinic receptor.
Mechanism of action of actin
The compound binds mnAChR, thus preventing the fixation of acetylcholine on the nicotinic receptor, while the receptor itself remains in a closed state. In this state, no sodium ions are released, so the muscles are in a state of relaxation and rest. The amino acids in snake venom block the body's production of neural mediators that cause muscle contraction. The amino acids prevent the muscles from contracting, which allows the desired smoothing effect to be achieved. Tripeptide has a similar action to snake venom toxins, so it is able to quickly relax facial muscles, smoothing out small wrinkles and preventing new ones from forming. It is a safe, natural analog of Botox. In addition, the product evens skin tone, lightens color and smoothes expression lines within a week of regular use.
The Swiss manufacturer says that the effect of Syn-ake is identical to that of Argireline because the peptide also prevents the transmission of nerve impulses to the facial muscles. However, scientific studies have proven that the Syn-ake component is much more powerful than Argireline.
Cosmetic properties of the ingredient, proven by tests
- Reduction of the depth of forehead wrinkles by approximately 52% in 28-30 days
- Reduction of the depth of mimic wrinkles on the skin around the eyes and mouth
- Skin tightening and smoothing
- Improvement of immunity
- Prevention of new wrinkles.
The effectiveness of studies that will make you want to buy Syn-Ake
If you decide to use cosmetics with peptides and want to see results - you should remember one important rule called "regularity". Peptides only work if they are applied daily. Then they accumulate in the skin and start to show visible effects after 14 days, reaching their maximum effectiveness after 28-30 days.
In vivo tests carried out by the manufacturer prove a noticeable result of wrinkle smoothing with regular use of the component. Wrinkles on the forehead, between the eyebrows and on the bridge of the nose, as well as under the eyes, nasolabial folds and neck wrinkles are smoothed.
In modern cosmetology, peptides represent the most promising direction in the fight against age-related skin changes. Today, many cosmetic brands produce cosmetic lines that contain the tripeptide Syn-ake in the composition. These include Purebess facial creams, Formula Syn-Ake serums, Deoproce Syn-Ake intensive anti-aging creams and lotions, and others.
Peptide application results

Effect of SYN®-AKE (4%) on smoothing (Ra) and wrinkle control (Rz and Rt) measured on the forehead after 28 days, compared to a competitive product (10%) and placebo.

Measurement of the smoothing effect (Ra) and wrinkle smoothing (Rz and Rt) of SYN®-AKE (4%) on hound's feet after 28 days.
| Товар | |
|---|---|
| Producer: | DSM |
| Appearance: | liquid |
| Solubility: | in water |
| Origin: | synthetic |
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